2026 ACCP Virtual Journal Club Webinar: Assessment of Hepatic Impairment and Implications for Pharmacokinetics of Substance Use Treatment

Live Session: Wednesday, April 22^nd, 2026, from 12:00 to 1:00 PM ET

On Demand: April 22^nd, 2026 to April 22^nd, 2029

Why is this webinar important to your practice? 

Learners that complete this webinar will have enhanced knowledge of the impact of hepatic impairment on drug metabolism and pharmacokinetics. This activity reviews the pathophysiology of liver disease and its effects on hepatic drug clearance, along with current approaches to assessing hepatic function, including the Child-Pugh classification, MELD score and emerging noninvasive techniques. Emphasis is placed on how hepatic impairment contributes to variability in drug exposure and informs dose selection, with application to clinical pharmacology and medications used in patients with liver dysfunction. This activity is designed to enhance knowledge of hepatic function assessment, interpretation of pharmacokinetic changes and application of evidence-informed dosing strategies to optimize patient outcomes

Target Audience:

Interprofessional team of Physicians, Pharmacists, PhDs and other health care professionals involved in clinical pharmacology and the care of patients with hepatic impairment.

Learning Objectives

After completing this activity, the learner will be able to: