Learners that complete this webinar will have enhanced knowledge of the impact of hepatic impairment on drug metabolism and pharmacokinetics. This activity reviews the pathophysiology of liver disease and its effects on hepatic drug clearance, along with current approaches to assessing hepatic function, including the Child-Pugh classification, MELD score and emerging noninvasive techniques. Emphasis is placed on how hepatic impairment contributes to variability in drug exposure and informs dose selection, with application to clinical pharmacology and medications used in patients with liver dysfunction. This activity is designed to enhance knowledge of hepatic function assessment, interpretation of pharmacokinetic changes and application of evidence-informed dosing strategies to optimize patient outcomes.

Learners who complete this activity will have strengthened knowledge of emerging digital health technologies and their application in clinical care and research. This activity reviews the convergence of extended reality (XR), artificial intelligence (AI), biosensing and digital twin technologies to enable more objective assessment, personalized interventions and improved patient outcomes. Content covers digital therapeutics, including regulatory pathways and reimbursement considerations, with emphasis on AI-driven, adaptive models and key challenges such as data variability, subjectivity of health outcomes and algorithmic fairness. This activity is designed to increase knowledge of digital health technologies and their potential to enhance clinical decision-making, patient monitoring and precision medicine approaches.